Factors Related to Congenital Heart Disease in Offspring from Women with Rheumatic Heart Disease: Case reports from Moi Teaching and Referral Hospital, Eldoret, Kenya-Reference-Cited by-同舟云学术

Factors Related to Congenital Heart Disease in Offspring from Women with Rheumatic Heart Disease: Case reports from Moi Teaching and Referral Hospital, Eldoret, Kenya

Published:2019-11-07 Issue:3 Volume:2 Page:87-92
ISSN:2582-0370
Container-title:Asploro Journal of Biomedical and Clinical Case Reports
language:en
Short-container-title:Asp Biomed Clin Case Rep

Author:

PA Philippe¹^ORCID,EO Orang’o¹,FA Barasa²

Affiliation:

1. Department of Reproductive Health, Moi University School of Medicine, P. O Box 4606-30100, Eldoret, Kenya

2. Department of Cardiology, Moi Teaching and Referral Hospital – Eldoret, Kenya, P.O Box 3-30100, Nandi Road, Eldoret, Kenya

Abstract

Maternal exposure to environmental factors has been reported to be associated with birth defects. Congenital heart defects are the most common and are associated with high morbidity and mortality in offspring. However, the relation of maternal rheumatic heart disease to congenital heart defects in the offspring is a rare event not yet reported. The authors report 2 cases of infants with congenital heart defects born from mothers with rheumatic heart disease. This study highlights factors related to congenital heart defects in both newborns.

Publisher

Asploro Open Access Publications

Reference18 articles.

1. Liu Y, Chen S, Zühlke L, Black GC, Choy MK, Li N, Keavney BD. Global birth prevalence of congenital heart defects 1970-2017: updated systematic review and meta-analysis of 260 studies. Int J Epidemiol. 2019 Apr 1;48(2):455-63. [PMID: 30783674]

2. Christianson A, Howson CP, Modell B. The hidden toll of dying and disabled children. March of Dimes. Global report on birth defects. 2006.

3. Blue GM, Kirk EP, Giannoulatou E, Sholler GF, Dunwoodie SL, Harvey RP, Winlaw DS. Advances in the Genetics of Congenital Heart Disease: A Clinician's Guide. J Am Coll Cardiol. 2017 Feb 21;69(7):859-70. [PMID: 28209227]

4. Hinton RB. Genetic and environmental factors contributing to cardiovascular malformation: a unified approach to risk. J Am Heart Assoc. 2013 Jun 18;2(3):e000292. [PMID: 23778188]

5. Schulkey CE, Regmi SD, Magnan RA, Danzo MT, Luther H, Hutchinson AK, Panzer AA, Grady MM, Wilson DB, Jay PY. The maternal-age-associated risk of congenital heart disease is modifiable. Nature. 2015 Apr 9;520(7546):230-33. [PMID: 25830876]