Affiliation:
1. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation, Russian Clinical and Research Center of Gerontology
2. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Abstract
This review article deals with the topic of changes in bone tissue in the process of aging of the body. Adipogenesis and osteogenesis are affected at the molecular level, proteins and genes are described, in which somatic mutation can occur during the aging process, resulting in both minor changes and an active loss of bone mineral density. The factors that affect the change in bone mineral density mainly in the elderly, and existing drugs that can slow down osteoporosis are listed. Knowledge of the cellular and molecular mechanisms underlying the aging of bone tissue will contribute to the creation of targeted therapy for osteoporosis, which slows down bone aging and prevents falls and fractures in the elderly people.
Publisher
Autonomous non-profit organization-Society of Specialists in the Field Innovative Medical Technology
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