Affiliation:
1. Pirogov National Research Medical University, Russian Gerontology Research and Clinical Centre
Abstract
Sarcopenia is a generalized progressive skeletal muscle disease that is associated with an increased risk of disability and death due to falls and fractures. The article details current information about the age-related features of metabolism and muscle tissue remodeling, which lead to the development of sarcopenia and its further progression. The possibilities of correcting sarcopenia are presented: the mechanism of action of experimental drugs acting on muscle tissue (myostatin, bimagrumab, landogrosumab) and non-drug methods of correcting sarcopenia (nutrition, physical activity) that have proven the effectiveness of non-drug methods for correcting sarcopenia (nutrition, physical activity) are analyzed, and the possible effects of taking vitamin D preparations for patients with sarcopenia are described.
Publisher
Autonomous non-profit organization-Society of Specialists in the Field Innovative Medical Technology
Reference62 articles.
1. Vollset S.E., Goren E., Yuan C.-W., et al. Fertility, mortality, migration, and population scenarios for 195 countries and territories from 2017 to 2100: A forecasting analysis for the Global Burden of Disease Study. Lancet 2020, 396, 1285–1306.
2. Rukovodstvo po klinicheskoi dietologii v geriatrii. Pod red. K.U. Beils, D.L. Loker, E. Zal'tsmana; Per. s angl.; Pod red. O.N. Tkachevoi. GEOTAR-Media, 2021 god, ISBN 978-5-9704-6464-9.
3. Fielding R.A., Vellas B., Evans W.J., Bhasin S., Morley J.E., Newman A.B., et al. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc. 2011;12(4):249–56.
4. Volpi E., Nazemi R., Fujita S. Muscle tissue changes with aging. Curr Opin Clin Nutr Metab Care. 2004;7(4):405–10.
5. Cruz-Jentoft A.J., Boirie Y., Cederholm T. et al. European Working Group on Sarcopenia in Older People. Report of the European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis // Age and Ageing. — 2010. — V. 39. — P. 412–423.
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献