Malignant Mesenchymal and Fibroepithelial Breast Tumors - Presentation of Three Cases

Abstract

Introduction: Malignant mesenchymal breast tumors, as is the case also with malignant phyllodes tumors, are rare malignancies that share several clinical and pathological characteristics. They are often locally aggressive and have a high potential for distant metastasis. This paper reports two cases of malignant phyllodes tumors and one case of breast sarcoma managed by our breast surgery team. One of the malignant phyllodes tumors showed rapid progression with early multiple visceral involvement and death. Discussion: Presentation of an updated review of the literature covering clinical, pathological, radiological and therapeutic considerations related to breast sarcomas and malignant phyllodes tumors. Conclusion: Breast sarcomas and malignant phyllodes tumors are rare breast malignancies that share more similarities than differences and require a multidisciplinary approach to management.