Blood pressure difference between regular hemodialysis and hemodialysis with hemoperfusion at Haji Adam Malik Hospital, Medan-Indonesia

Abstract

Background: The differences of Hemodialysis and Hemoperfusion’s  combination can increase of Uremic Toxin clearance, average creatinine clearance, and Angiotensin elimination optimally. The hemodialysis and hemoperfusion’s  combination also can decrease blood pressure and reduce the use of Anti Hypertension drugs so that the number of cardiac events in CKD patients may decrease. The use of ABPM is chosen because this is the best method of automatic blood pressure which has the most accurate blood pressure measuring periodically.Objective: This study aims to determine the difference of regular Hemodialysis and Hemodialysis with Hemoperfusion on blood pressure measured by using ABPM in Medan, North of Sumatra.Methods: This study was a pre-experimental study which conducted since December 2013-March 2014 to the 20 regular hemodialysis patients. The measurement included anamnesis, height, weight, systolic and diastolic blood pressure among patients with regular hemodialysis and hemodialysis with hemoperfusion. Results: The study found that about 3 of 20 subjects were out of the study. There was no significant difference found in systolic and diastolic blood pressure between regular hemodialysis and hemoperfusion group (P = 0.807 and 0.906, respectively) based on the T-paired test and Wilcoxon test. Conclusion: There was no significant difference between blood pressure measured using ABPM on the combination of hemodialysis and hemoperfusion compared with regular hemodialysis