Correlation between Urea Creatinine Ratio (UCR) and lipid profile in COVID-19 patients

Abstract

Background: SARS-CoV-2, as the leading cause of COVID-19 disease, can cause kidney disorders characterized by the presence of hematuria, increased creatinine, and other kidney pathological conditions. Since a 24-hour urine examination as the gold standard for urea examination has several weaknesses, it is necessary to carry out an alternative examination method especially, the Urea Creatinine Ratio (UCR). This study evaluates the correlation between UCR and lipid profile in COVID-19 patients.Methods: A descriptive-analytical design with a cross-sectional approach is applied. COVID-19 patients with positive PCR were examined for UCR, Total Cholesterol, Triglycerides, HDL, and LDL. The assessment was based on clinical chemistry analysis using an automatic analyzer. We perform a normality test using Shapiro-Wilk. The Pearson correlation test is used to see a correlation between variables. The study was conducted at Siloam Hospital in April-August 2021. Data were analyzed using SPSS version 20 for Windows.Results: There was no significant difference between UCR and the other variables based on the statistical analysis test (p>0.05). There was no significant correlation between UCR and cholesterol total (p= 0.230), UCR and Triglyceride (p= 0.680, UCR and HDL (p=0.970) and UCR and LDL (p= 0.190).  Conclusion: There is no significant correlation between UCR and lipid profile in COVID-19 patients