Correlation between clinical characteristics of colorectal cancer and nutritional status in patients undergoing surgery

Abstract

Background: The incidence of colorectal cancer in Indonesia reaches 12.8 per 100,000 adult population and is the cause of 9.5% of cancer deaths. 40–80% of all colorectal cancer patients are malnourished. This study aims to determine the prevalence of nutritional status in colorectal cancer and the correlation between clinical characteristics of colorectal cancer and nutritional status in patients undergoing surgery. Methods: This research is an observational study with a cross sectional method. The reachable population of this study was colorectal cancer patients who underwent surgery at dr. Cipto Mangunkusumo Hospital, Jakarta and admission will occur from September-December 2022 with predetermined inclusion and exclusion criteria. The instrument used is the Mini Nutritional Assessment (MNA)—bivariate data analysis using Chi-square followed by a multivariate logistic regression test. Results: There were 71 patients diagnosed with colorectal cancer at RSUPN dr. Cipto Mangunkusumo, in the September-December 2022 period, will undergo surgery. Clinical characteristics of colorectal cancer patients showed that most patients were 64-78 years old (57.7%) and male (52.1%). For clinical stages, it can be seen that the majority of patients have stages III and IV (78.9%), with a large tumor mass of 1-10.9 cm (76.1%), and the location of the cancer is in the rectum (59.2%) ). The results of CA19-9 levels show that most patients with normal CA19-9 levels (62.0%) and CEA levels were increased (66.2%). While the nutritional status of colorectal cancer, most of them have at risk of being malnourished (52.1%), followed by having malnourished (43.7%). The bivariate test results showed that the tumor size was significant (p <0.05). Conclusion: Most colorectal cancers are at risk of malnourished and there is a statistically strongest correlation between tumor mass and nutritional status in patients undergoing surgery.