Decreased Expression in Gastric Cancer and Its Clinical Significance Using VIKOR Method

Abstract

Many cancer-related mortalities are caused by tumour invasion and metastases, which are crucial steps in developing the malignant tumour phenotype. The most significant predictive factor at detection is now the diagnostic stage, depending on the DNM grading system, and the underlying basis behind the development and spread of bladder cancer is still unknown. Hence, additional research on the diagnostic factors linked to the spread and metastasis of stomach cancer would be useful. The production of FENDRR in gastrointestinal cancer cell lines and tissues was compared to that of normal mucosal cells and nearby non-tumour organs using real-time amplicon chain reaction (PCR). The pharmacological effect of FENDRR on gastrointestinal cancer cells was examined using cell viability assays, wound healing tests, and in vitro and in vivo invasive and migration experiments. To evaluate fibronectin1 mRNA and antigen translation, three methods were used: real-time PCR, western blot, and microscopy. Methodology: Antibody, Visualizing, Dilution, Fixative. Assessment options: CD4, CD1a, Q-Bend 10, CD31, Ki67, Tissue transglutaminase. From the end based on Q-Bend 10, the results showed that it received the highest rank, whereas CD4 had the lowest rank. The value of the dataset for decreased expression in the VIKOR method shows that Q-Bend 10 results in the top ranking.