A comparison analysis using the MCDM technique using Hydrogel-Based Drug Delivery Nanoparticles as Traditional Therapeutic Approaches to Cancer Tumors

Abstract

Uncontrolled division of abnormal cells in a particular region of the body leads to cancer, a disease that worsens or kills off cells. This could result in the recipient carrier dying. The majority of cancer patient deaths have been associated with the systematic administration of therapeutic agents (chemotherapy) and other conventional methods, which is the preferred treatment approach for cancer therapy. The mortality of this therapy is associated with side effects, off-target accumulation, toxicity, and rapid renal and hepatic clearance. Scientists have recently studied tumor site targeting and better retention of constant drug delivery to tumors in order to minimize side effects and toxicity-related challenges. Ingenious drug delivery methods for cancer therapy have been developed by scientists and researchers using water-containing polymers known as hydrogels. These drug transport systems' network-like structure and biological tissue-like consistency allow the drugs loaded into them to remain in a relatively stable condition. This study compares hydrogel-based drug delivery systems with other conventional cancer therapy approaches using the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) way of multicriteria decision making (MCDM). Based on specific criteria with given importance weights, a comparison is made. This study shows that by offering additional alternatives and criteria with availability and significance weights, the approach taken can be made more helpful and helpful in offering remedies to healthcare decision-makers facing ambiguous problems. Individual cancer sufferers' specific medical conditions.