Possible effects of coronavurus infection (COVID-19) on the cardiovascular system

Author:

Larina VN1ORCID,Golovko MG1ORCID,Larin VG1ORCID

Affiliation:

1. Pirogov Russian National Research Medical University, Moscow, Russia

Abstract

Acute viral respiratory infections can increase the risk of progression of a pre-existing condition, including a cardiovascular pathology. Life-threatening complications of Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitate research into the cardiovascular effects of COVID-19 crucial for developing adequate treatment strategy for infected patients, especially those of advanced age. This article reviews the literature on the clinical and functional characteristics of patients with COVID-19, including those with poor outcomes. The article looks at the pathophysiological processes occurring in the cardiovascular system in the setting of SARS-CoV-2 infection, risk factors and death predictors. It also discusses continuation of therapy with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in patients with COVID-19.

Publisher

Pirogov Russian National Research Medical University

Subject

General Medicine

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