Gestational Diabetes in Malaysia: A Systematic Review of Prevalence, Risk Factors and Outcomes

Author:

Cheong Lieng Teng,Foo Ken Yong,Ka Mun Lum,Shen Yung Toh,Chan Xuan Hii,Sivalingam Nalliah

Abstract

Gestational diabetes mellitus (GDM) is glucose intolerance first diagnosed during pregnancy. In Malaysia, the prevalence, risk factors, and maternal/foetal outcomes vary somewhat among the local studies. In this systematic review of Malaysian studies, we synthesise relevant data from 13 journal articles (including 10,285 women with gestational diabetes). A meta-analysis of twelve datasets showed a prevalence of 21.5% (95% CI 17.3 to 25.9%, random effect model). Clinical factors in the mother found to increase her risk of GDM were consistent with international data. A meta-analysis of complications showed statistically significant increase for macrosomia (OR 3.08, 95% CI 1.77 to 5.36) but not for pre-eclampsia (OR 1.44, 95% CI 0.52 to 4.00) and caesarean delivery (OR 1.31, 95% CI 0.98 to 1.75). The high prevalence of gestational diabetes mellitus and documented adverse consequences support the need for universal screening of this condition in all pregnant women in Malaysia.

Publisher

Penerbit Universiti Kebangsaan Malaysia (UKM Press)

Subject

Multidisciplinary

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