Immunomodulator effect of ketamine on rat models of sepsis (fecal induced peritonitis): Eosinophil and monocyte modulation
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Published:2020-07-15
Issue:3
Volume:24
Page:
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ISSN:2220-5799
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Container-title:Anaesthesia, Pain & Intensive Care
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language:
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Short-container-title:APIC
Author:
Asmoro Aswoco Andyk,Jaya Wiwi,Nasiqah Asna,Rodli Muhammad
Abstract
Sepsis is a result of dysregulated inflammation and it affects the inflammatory mediator cell production. Ketamine has an immunomodulatory effect and it can be used in the sepsis immunotherapy. We conducted this study to determine the effect of ketamine on the number of eosinophils and monocytes in the rat model of sepsis.
Publisher
Aga Khan University Hospital
Subject
Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine