Epigenetics and multifactorial diseases

Author:

Vokhmyanina N. V.1

Affiliation:

1. North-Western State Medical University named after I. I. Mechnikov,

Abstract

At present, epigenetics is being studied in detail and actively, and the significance of epigenetics in the development of multifactorial diseases has been determined. In this regard, a large number of publications have recently appeared that analyze the results of studies using epigenetic markers. The obtained promising results indicate the possibility of early detection and prediction of many multifactorial diseases. This review briefly outlines the theoretical foundations of epigenetics and epigenetic mechanisms. The participation of epigenetics in the formation of multifactorial pathology is considered on the example of celiac disease, multiple sclerosis and cardiovascular diseases, confirmed by the identified epigenetic markers.

Publisher

Arterialnaya Gipertenziya

Reference27 articles.

1. Waddington CH. The epigenotype. 1942. Int J Epidemiol. 2012 Feb;41(1):10. DOI: 10.1093/ije/dyr184. Epub 2011 Dec 20. PMID: 22186258.

2. Shchuko AG, Veselov A A, Yurieva TN, et.al, Epigenetics and methods of its realization Sibirskij nauchnyj medicinskij zhurnal = Siberian Scientific Medical Journal. 2017;37(4):26–35. In Russian

3. Smirnov VV, Leonov GE. Epigenetics: theoretical aspects and practical value Lechaschi Vrach. 2016;(12):26–30. In Russian

4. Patkin EL, Quinn J. Epigenetical mechanisms of susceptibility to complex human disease Ecological genetics. 2010. Vol. VIII, № 4. P. 44–56. In Russian

5. Patkin EL, Sofronov GA. Environment-dependent human disease: the epigenetic mechanisms of their development and inheritance Medical academic journal. 2015. Vol. 15. N. 3. P. 7–23. In Russian

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3