Atrial fibrillation with debut in childhood, probably associated with variant D1907H in the SCN10a gene

Author:

Kovalchuk T. S.1,Kostareva A. A.1,Sivushchina Е. S.1,Vershinina T. L.1,Chueva K. A.1,Pervunina T. M.1,Tatarskiy E. S.1,Fetisova S. G.1,Vasichkina E. S.1

Affiliation:

1. Ministry of Health of the Russian Federation

Abstract

   Atrial fibrillation is the most common persistent arrhythmia in adults; however, it is quite rare in children. In patients without structural heart diseases or extracardiac causes, the genetic basis of the arrhythmia can be assumed. A clinical case of atrial fibrillation in a child, probably associated with the variant D1907H in the SCN10A gene, was described in this article. In spite of a very limited clinical and genetic information on the association of Nav 1.8 channel encoded by SCN10A with atrial arrhythmias, the presented case can further confirm the role of this gene in arrhythmogenesis in children.

Publisher

Arterialnaya Gipertenziya

Reference22 articles.

1. Hindricks G., Potpara T, Dagres N, et al. ESC Scientific Document Group, 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur Heart J. 2021;42(5):373–498. DOI: 10.1093/eurheartj/ehaa612. Erratum in: Eur Heart J. 2021; 42 (5): 507. Erratum in: Eur Heart J. 2021; 42 (5): 546–547. Erratum in: Eur Heart J. 2021;(40):4194.

2. Benjamin E. J., Muntner P., Alonso A., et al. American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2019 Update: A Report From the American

3. Heart Association. Circulation. 2019; 139 (10): e56–e528. DOI: 10.1161/CIR.0000000000000659. Erratum in: Circulation. 2020; 141 (2): e33.

4. Gourraud J. B., Khairy P., Abadir S., et al. Atrial fibrillation in young patients. Expert Rev Cardiovasc Ther. 2018; 16 (7): 489–500. DOI: 10.1080/14779072.2018.1490644.

5. Brugada J., Blom N., Sarquella-Brugada G., et al. European Heart Rhythm Association; Association for European Paediatric and Congenital Cardiology. Pharmacological and non-pharmacological therapy for arrhythmias in the pediatric population: EHRA and AEPC-Arrhythmia Working Group joint consensus statement. Europace. 2013; 15 (9): 1337–82. DOI: 10.1093/europace/eut082.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3