Characteristics, Management, and In-Hospital Outcomes of Diabetic Patients with Acute Coronary Syndrome in the United Arab Emirates

Author:

Shehab Abdulla1,Al-Dabbagh Bayan1,Almahmeed Wael2,Bustani Nazar2,Agrawal Amrish3,Yusufali Afzal4,Wassef Adel5,Alnaeemi Abdulla6,Alsheikh-Ali Alawi A.27

Affiliation:

1. Department of Internal Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain, UAE

2. Heart and Vascular Institute, Sheikh Khalifa Medical City, P.O. Box 51900, Abu Dhabi, UAE

3. Department of Cardiology, Fujairah Hospital, P.O. Box 10, Fujairah, UAE

4. Dubai Heart Centre, Dubai Hospital, P.O. Box 7272, Dubai, UAE

5. Obaidallah Hospital (Saif Hospital), MOH, P.O. Box 4727, Ras Al-Khaimah, UAE

6. Department of Cardiology, Zayed Military Hospital, P.O. Box 3740, Abu Dhabi, UAE

7. Institute for Clinical Research and Health Policy Studies and Tufts University School of Medicine, Boston, MA 02111, USA

Abstract

We describe the baseline characteristics, management, and in-hospital outcomes of patients in the United Arab Emirates (UAE) with DM admitted with an acute coronary syndrome (ACS) and assess the influence of DM on in-hospital mortality. Data was analyzed from 1697 patients admitted to various hospitals in the UAE with a diagnosis of ACS in 2007 as part of the 1st Gulf RACE (Registry of Acute Coronary Events). Of 1697 patients enrolled, 668 (39.4%) were diabetics. Compared to patients without DM, diabetic patients were more likely to have a past history of coronary artery disease (49.1% versus 30.1%,P<0.001), hypertension (67.2% versus 36%,P<0.001), and prior revascularization (21% versus 11.4%,P<0.001). They experienced more in-hospital recurrent ischemia (8.5% versus 5.1%;P=0.004) and heart failure (20% versus 10%;P<0.001). The mortality rate was 2.7% for diabetics and 1.6% for nondiabetics (P=0.105). After age adjustment, in-hospital mortality increased by 3.5% per year of age (P=0.016). This mortality was significantly higher in females than in males (P=0.04). ACS patients with DM have different clinical characteristics and appear to have poorer outcomes.

Publisher

Hindawi Limited

Subject

General Environmental Science,General Biochemistry, Genetics and Molecular Biology,General Medicine

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