Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis-Reference-Cited by-同舟云学术

Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis

Published:2006 Issue: Volume:6 Page:460-465
ISSN:1537-744X
Container-title:The Scientific World JOURNAL
language:en
Short-container-title:The Scientific World JOURNAL

Author:

Hellwig Kerstin¹,Lukas Carsten¹,Brune Niels¹,Hoffmann Volker¹,Schimrigk Sebastian¹,Przuntek Horst¹,Müller Thomas¹

Affiliation:

1. Department of Neurology, St. Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany

Abstract

We describe four patients with relapsing remitting multiple sclerosis (RRMS) who experienced a relapse with acute onset of painful sensations. Pain sensations disappeared in two of them and markedly reduced in the other ones after repeat application of intrathecal triamcinolone acetonide (TCA) following a prior unsuccessful treatment with intravenous steroids. TCA administration was well tolerated and no serious side effects occurred. Repeated intrathecal TCA injection may provide a substantial benefit in RRMS patients with acute onset of pain due to an inflammatory lesion within the spinal cord.

Publisher

Hindawi Limited

Subject

General Environmental Science,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://downloads.hindawi.com/journals/tswj/2006/931651.pdf

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