Chemokines-Reference-Cited by-同舟云学术

Chemokines

Published:2007 Issue: Volume:7 Page:224-232
ISSN:1537-744X
Container-title:The Scientific World JOURNAL
language:en
Short-container-title:The Scientific World JOURNAL

Author:

Horuk Richard¹

Affiliation:

1. Department of Immunology, Berlex Biosciences, Richmond, CA, USA

Abstract

Chemokines are a family of polypeptides that direct the migration of leukocytestoward a site of infection. They play a major role in autoimmune disease and chemokine receptors have recently been found to mediate HIV-1 fusion. In this short review we examine the role of chemokines in host defence and in the pathophysiology of autoimmune diseases. We conclude by discussing various therapeutic approaches that target chemokine receptors and that could be beneficial in disease.

Publisher

Hindawi Limited

Subject

General Environmental Science,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://downloads.hindawi.com/journals/tswj/2007/692543.pdf

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