Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders-Reference-Cited by-同舟云学术

Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders

Published:2007 Issue: Volume:7 Page:888-902
ISSN:1537-744X
Container-title:The Scientific World JOURNAL
language:en
Short-container-title:The Scientific World JOURNAL

Author:

Masini Emanuela¹,Bani Danielle²,Marzocca Cosimo¹,Mateescu Mircea Alexandru³,Mannaioni Pier Francesco¹,Federico Rodolfo⁴,Mondovì Bruno⁵

Affiliation:

1. Department of Preclinical and Clinical Pharmacology, University of Florence, Italy

2. Department of Anatomy, Histology and Forensic Medicine, Section of Histology, University of Florence, Italy

3. Department of Chemistry and Biochemistry, Université du Québec à Montréal, Montreal (Quebec), Canada

4. Department of Biology, University of Rome, Italy

5. Department of Biochemical Sciences “A. Rossi Fanelli”, Rome University “La Sapienza”, Rome, Italy

Abstract

Amine oxidases (AOs) are ubiquitous enzymes involved in the metabolism of biogenic amines. Copper AOs (Cu-AOs) catalyze the oxidative deamination of primary amine groups of several biogenic amines, such as putrescine, cadaverine, and histamine. In the present review, the effects of a plant amine oxidase (Cu-AO, histaminase, EC1.4.3.6) purified from pea seedlings in the modulation of IgE-mediated allergic reactions, and in the prevention of cardiac and splachnic postischemic reperfusion damage are reported.

Funder

Ente Cassa di Risparmio di Firenze

Publisher

Hindawi Limited

Subject

General Environmental Science,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://downloads.hindawi.com/journals/tswj/2007/408423.pdf

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