The Diagnostics Technologies and Control of COVID-19

Abstract

The coronavirus outbreak 2019 (COVID-19) is a global pandemic triggered by the extremely infectious SARS-CoV-2 virus, which is currently the world's most dreadful viral disease. Early identification, evaluation, separation, and recovery would be the most helpful ways to avoid and monitor COVID-19. After the pandemic outbreak, the reverse transcription-polymerase chain reaction (RT-PCR) approach has become a common diagnostic technique of widespread clinical use. However, the extensive usage of traditional diagnostic tools in the light of COVID-19's rapid dissemination is limited by several limitations. As a result, the rapid increase in the number of COVID-19 patients necessitates the development of alternative technologies. In this regard, we summarise many advances in molecular diagnostics technologies such as nucleic acid detection-based techniques, serological systems for detecting antibodies against SARS-CoV-2, lateral flow immunoassay (LFIA), CRISPR, and metagenomics strategies that have proven to work well in COVID-19 diagnostics and may become a reliable alternative to traditional laboratories. These alternate technologies are highly resilient and precise, assisting us in making correct diagnoses and limiting the spread of COVID-19 infection. The overall conclusion of the proposed article speculates how different treatments, such as antiviral therapies, immunomodulatory therapies, Convalescent Plasma Therapy (CPT), and Several Vaccinations, have been successful in the care and control of COVID-19.