Antibacterial Activity of Thiazole and its Derivatives: A Review

Abstract

Thiazoles are one of the most intensively scrutinized classes of 5-membered aromatic heterocycles. Many natural and synthesized thiazole and its derivatives showed significant biological activity. Due to its unique properties, thiazole derivatives show significant antibacterial activity against various bacteria and pathogens. Thus, the present review ascribes the antibacterial activity of various thiazole and its derivatives. From using various databases, all the relevant literature has been reviewed. The review was deliberated based on the significant papers on the antibacterial activity of thiazole derivatives. Thiazole and its derivatives, a significant class of heterocyclic derivatives, have played an important role in chemical sciences. Due to their unique properties, they play an important role in the pharmaceutical industry. Thiazole and its derivatives show significant anticancer, anti-tuberculous, antioxidant, and anti-inflammatory activities. Due to their tremendous biological significance, scientists are actively engaged in designing new biological active thiazole derivatives. This review emphasized the antibacterial properties of various thiazole and its derivatives. The present study will help researchers design and synthesize various biological active molecular probes and study their antibacterial properties using various processes against various bacteria and pathogens.