Synthesis and Characterization of Wound Dressing Material from Bio-Wastes Impregnated with the Spider Web and the Ethanolic Weaves Extract of Mangifera indica (L.)

Abstract

Substantial progress in wound therapy has not snuffed out the passion in search of innovative wound dressing materials. This work is to analyze the physiochemical characterizations and biological evaluation of a wound dressing material. A wound dressing material had been synthesized from Physiologically Clotted Fibrin (PCF), Fish Scale Collagen (FSC). Also, the wound dressing material had impregnated with the folklore medicinal impact of the Spider Web (SW) and the Ethanolic Extract of Mangifera indica (L.)(EEMI). Infrared spectroscopic techniques confirmed the presence of Type I collagen. Surface morphology established the smooth, uniform, porous, biocompatible surface of the material. Water absorption studies, porosity measurements showed the required characteristics, the antibacterial activity favored the resistance, and the ash test supported the eco-friendly environment of the wound dressing material. Human erythrocytes had reviewed biocompatibility. The supernatant of the wound dressing material at different concentrations and incubation times had determined for percent hemolysis. Plots between percent hemolysis and concentration showed the non-hemolytic behavior of the wound dressing material. The synthesized biomaterial could propose as a wound dressing material with good efficacy, cost-effectiveness, and eco-friendly. The synthesized biomaterial could have been a better wound dressing material with good efficacy, cost-effectiveness, and eco-friendly.