Toxicity Studies of Centella asiatica for Drug Development: Mini Review

Abstract

Toxicity studies' quality control of drug plant-based products is an important aspect of pharmacological research. The purpose of this literature review is to extract about toxicity test on Centella asiatica. The plant component utilized, the test animals used, the type of toxicity test, evaluation, the findings, and conclusions of each test are all included in this review—the database used in PubMed. Most of the literature results obtained from this review indicate high safety in C. asiatica plants. The acute toxicity test is that the most frequently used toxicity test. The use varies from plant parts to whole plants, with minimal side effects reported and high in safety, so it can be concluded that C. asiatica is very prospective to be developed as a medicine.