Mini-Review on Phytochemistry and Pharmacological Studies of Piper regnellii (Miq.) C.DC.

Abstract

Piper regnellii (Miq.) C.DC. is an herbaceous plant that can be found in tropical and subtropical regions of the world and commonly employed in folk medicine for the treatment of wounds, swellings, and skin irritations. In particular, phytochemical studies on P. regnellii have yielded essential oils, benzofuran neolignans, and phenylpropanoids, while the extracts and compounds demonstrated a broad spectrum of pharmacological activities. The present study aims to provide a review of previously published studies conducted on both the phytochemistry and pharmacological activities of P. regnellii. Accordingly, the scientific journals used for this brief literature review were obtained from various electronic sources, including Science Direct, PubMed, Google Scholar, Scopus, and Web of Science. In particular, the outcome of this review is expected to support the therapeutic potential of P. regnellii further as well as provide convincing evidence to its future clinical applications in modern medicine. Overall, this is aimed to increase the amount of data that supports the application and exploitation of new drug development.