Morphological substantiation of laser exposure parameters and modes for surgical treatment of intrauterine pathology

Abstract

Introduction No data on experimentally substantiated parameters and modes of diode laser radiation allowing a minimally traumatic surgical treatment of intrauterine pathology have been found in the literature.The aim of the investigation was to substantiate experimentally the optimum parameters and modes of diode laser radiation in the treatment of intrauterine pathology based on the study of morphological changes in the endometrium.Materials and methods 48 endometrial samples were exposed to 10-40 W diode laser power in a constant mode and 15 samples - in a pulsed mode with 3 different sets of laser exposure parameters. The data were statistically processed using Microsoft Excel spreadsheets, version 16.49. The differences were considered statistically significant at р<0.05.Results Width of the ablation zone, lateral coagulation and hyperthermic exposure zone was calculated at the most optimal parameters of laser energy (20 W), achieving adequate cutting and bleeding properties of the laser. The most effective in the pulsed mode of laser operation was 30 W amplitude power of radiation, the pulse duration of 100 ms, the duration of the interval between pulses of 50 ms, the average power of 20 W.Discussion Comparative analysis of morphometric parameters in the action of laser radiation in the constant mode with a radiation power of 20 W and in the pulsed mode with an average laser power of 20 W has shown that the structural parameters have significantly lower values in the pulsed laser mode.Conclusion Optimal cutting properties of the laser are observed when constant laser irradiation with a power of 20 W is used. The best cutting and bleeding properties were demonstrated by the pulsed laser mode with an average power of 20 W, amplitude power of 30 W, pulse duration of 100 ms, and inter-pulse interval of 50 ms.