Affiliation:
1. Saint Petersburg State Pediatric Medical University; First Saint Petersburg State Medical University n. a. I. P. Pavlov
2. First Saint Petersburg State Medical University n. a. I. P. Pavlov; Institute of Experimental Medicine
3. Saint Petersburg State University
Abstract
In the light of modern ideas about the pathogenesis of non-alcoholic fatty liver disease (NAFLD), along with the decoding of the genetic polymorphism of genes that regulate lipid and carbohydrate metabolism, immune factors, metabolic disorders and inflammation, a key role in the pathogenesis of the disease belongs to the intestinal microbiota, which takes part in development of all stages of NAFLD. The article presents the pathogenetic relationships of intestinal microbiota and metabolic disorders.
Subject
Materials Chemistry,Economics and Econometrics,Media Technology,Forestry
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