Affiliation:
1. Tambov State University n. a. G. R. Derzhavin
2. PET-Technology Cо., Centre for Nuclear Medicine
Abstract
Positron emission tomography combined with computer tomography (PET/CT) is considered as a noninvasive method for evaluation in lung cancer. SUVmax provides information on biological aggressiveness, key pathological features and potential of tumor spread. However, standardized and generally accepted criteria for determining malignant and benign lymph nodes do not exist, which is a common problem for molecular diagnostics physicians and generates clinical demand, since the standardization of these criteria has the potential to improve diagnostic accuracy, comparability between research and a general understanding by clinicians. To this end, we tried to determine the diagnostic accuracy of the maximum standardized absorption value (SUVmax) for mediastinal lymph nodes, compare the ability to predict mediastinal malignancy: SUVmax, the ratio of SUVmax l node to SUVmax of the primary tumor (SUVmaxN/SUVmaxT), and also SUVmaxN/SUVmaxT multiplied by maximum tumor diameter (SUV index).
Subject
Materials Chemistry,Economics and Econometrics,Media Technology,Forestry
Reference20 articles.
1. Sostoyanie onkologicheskoi pomoshchi naseleniyu Rossii v 2016 godu. Pod red. A. D. Kaprina, V. V. Starinskogo, G. V. Petrovoi — M.: MNIOI im. P. A. Gertsena — filial FGBU «NMIRTs» Minzdrava Rossii, 2017. — ill. — 236 s.
2. Methods for Staging Non-small Cell Lung Cancer: Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
3. Quint LE, Francis IR, Wahl RL, Gross BH, Glazer GM. Preoperative staging of non-small cell carcinoma of the lung: imaging methods. AJR Am J Roentgenol. 1995;164:1349–59.
4. Kyoichi Kaira et al. Biological significance of 18F-FDG uptake on PET in patients with non-small-cell lung cancer
5. Cuaron J, Dunphy M, Rimner A. Role of FDG-PET scans in staging, response assessment, and follow-up care for non-small cell lung cancer. Front Oncol. 2013;2:208.