Analysis of risk factors and hypoxic-ischemic damage consequences to central nervous system in newborns

Abstract

Perinatal damage to the central nervous system (CNS) is currently a pressing issue within the structure of neonatal pathology, leading to the development of various neurological complications and causing disability and death.The purpose. Identifying risk factors contributing to perinatal third-degree hypoxic-ischemic damage of the CNS in newborns and to examine the data of clinical, laboratory and instrumental studies.Results. In the course of this study, it was revealed that the leading syndromes at the birth of the majority of infants from the main group were the suppression syndrome and the syndrome of muscular hypotension. The highest proportion among extragenital pathologies was represented by infectious diseases of various etiologies, which the newborns’ mothers had suffered during pregnancy and childbirth. Most commonly reported pregnancy complications in mothers of the main group were anemia, fetal bladder abnormality and premature rupture of fetal membranes. Neurosonography revealed subependymal cysts, signs of cerebral ischemia and ventriculomegaly as most сommonly visualized abnormalities.Conclusions. It was established during the study that the primary risk factors for the development of hypoxic-ischemic damage to the CNS were complications during pregnancy and infectious diseases of various etiologies, which the mothers had suffered during pregnancy and childbirth.