Affiliation:
1. Central State Medical Academy of the Administrative Department of the President of Russia
2. Lyubertsy Dermatovenerologic Dispensary
Abstract
In recent years, issues of the complex use of phototherapy methods and drugs in the treatment of patients with rosacea and acne have been actively developed and studied. Due to the wide range of therapeutic effects, IPL therapy has theoretical prerequisites for use in these diseases. However, many issues of efficacy and safety of the combined use of topical drugs and broadband pulsed light remain open and require further study. The article presents data on the effectiveness of combined methods. The study included 45 patients diagnosed with rosacea with a combination of erythematous-telangiectatic subtype and papulo-pustular subtype. All patients received the following therapy: Mirvaso® Derm – one time per day in the morning, Solantra® – 1 time per day at night, specialized Cetaphil® dermatocosmetics. All patients underwent IPL-therapy one time in 3 weeks, the average course was 4–6 procedures. In accordance with the dynamics of Dermatological Index Scale of Symptoms (DISS), 37 (82.2 %) patients managed to fully control the process, 8 (17.8 %) showed significant improvement. It should be noted that not a single patient interrupted treatment, which indicates the high safety of the complex method of therapy. Also under observation were 19 patients with papulopustular acne of moderate severity, who were prescribed complex therapy: A fixed combination of BPO + adapalene (Effezel®) – one time per day in the evening, specialized Cetaphil® dermatocosmetics on an ongoing basis and IPL therapy a time per day for a four week period, the course consisted of four procedures. The dynamics of the total APSEA score was 74.6 %. Thus, all patients noted the high efficiency of the complex method, which was confirmed by a pronounced positive effect on the quality of life. These own data confirm the feasibility of an integrated approach in the treatment of patients with both rosacea and acne.
Subject
Materials Chemistry,Economics and Econometrics,Media Technology,Forestry
Reference20 articles.
1. Acne and rosacea. Edited by Kruglova L. S. GEOTAR-Media. 2021. 207 p.
2. Sharshunova A. A., Kruglova L. S., Kotenko K. V., Sofinskaya G. V. Etiopathogenesis and possibilities of laser therapy for erythematous-telangiectatic subtype of rosacea. Physiotherapy, Balneology, Rehabilitation. 2017. Vol. 16. No. 6. P. 284–290.
3. Muto Y., Wang Z., Vanderberghe M., Two A., Gallo R. L., Di Nardo A. Mast cells are key mediators of cathelicidin-initiated skin inflammation in rosacea. J. Investig. Dermatol. 2014. 134: 2728–2736.
4. Clinical guidelines. Rosacea. Russian Society of Dermatovenerologists and Cosmetologists. 2020.
5. Agafonova E. V., Kruglova L. S., Sofinskaya G. V. Rosacea: Current issues of therapy with the use of physical factors. Physiotherapist. 2018. No. 4. P. 23–33.