Evaluation of the proliferative activity of cell cultures on nanostructured coatings for dental implants-Reference-Cited by-同舟云学术

Evaluation of the proliferative activity of cell cultures on nanostructured coatings for dental implants

Published:2022-10-15 Issue:22 Volume: Page:7-10
ISSN:2078-5631
Container-title:Medical alphabet
language:
Short-container-title:Medicinskij alfavit

Author:

Dolgalev Al. Al.¹^ORCID,Choniashvili D. Z.²,Yusupov R. D.³^ORCID,Ambartsumov M. G.⁴^ORCID,Didenko N. N.¹^ORCID,Sergeev Y. A.⁵^ORCID

Affiliation:

1. LLC «Implant Additive Technologies»; Stavropol State Medical University of the Ministry of Health of the Russian Federation

2. North Ossetian State University named after Kosta Levanovich Khetagurov (SOGU)

3. Pyatigorsk Medical and Pharmaceutical Institute-branch of the Volgograd State Medical University

4. North Caucasus Federal University

5. LLC «Implant Additive Technologies»

Abstract

The success of implantation treatment largely depends on osseointegration – a stable connection of bone tissue cells with the implant surface. One of the key technical factors on which successful osseointegration depends is the biocompatible surface of the implant.Materials and methods. The authors investigated three series of coatings on prototypes (samples) of titanium implants for biological compatibility: titanium dioxide (TiO2) films obtained by plasma activated atomic layer deposition (PEALD); titanium dioxide (TiO2) films obtained by sol-gel method; diamond-like carbon (DLC) films. Primary cultures of MSCs – mesenchymal stromal cells of rat adipose tissue were used to study proliferative activity.Results. A total of 30 samples were examined, samples made of titanium grade VT6 without coating served as a control. Samples, TiO2 ALD 25 nm, DLC 100 nm and DLC 200 nm, on which cellular elements showed significantly high levels of proliferative activity showed high biological compatibility.

Publisher

Alfmed LLC

Subject

Materials Chemistry,Economics and Econometrics,Media Technology,Forestry

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