Affiliation:
1. Russian National Research Medical University n. a. N. I. Pirogov
2. Medical and Sanitary Unit No. 152 of the Federal Medical and Biological Agency
Abstract
The majority of agranulocytosis cases are caused by drugs, including nonsteroidal anti-inflammatory drugs, antibiotics, antithyroid agents, etc. Here, we report a case of severe agranulocytosis in a 67-year-old woman following nonsteroidal anti-inflammatory therapy which was successfully managed using recombinant human granulocyte colony-stimulating factor. Although metamizole, has been in use since 1922 in the management of postoperative pain, colic pain, cancer pain and migraine, agranulocytosis as a direct side effect of metamizole therapy has been rarely reported. It is important to keep in mind this rare but potentially life-threatening adverse effect of metamizole, when initiating therapy.
Subject
Materials Chemistry,Economics and Econometrics,Media Technology,Forestry
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