Contraceptive and therapeutic effects of combined oral contraceptive with drospirenone-Reference-Cited by-同舟云学术

Contraceptive and therapeutic effects of combined oral contraceptive with drospirenone

Published:2020-09-21 Issue:16 Volume: Page:6-9
ISSN:2078-5631
Container-title:Medical alphabet
language:
Short-container-title:Medicinskij alfavit

Author:

Ovsyannikova T. V.¹,Kulikov I. A.¹

Affiliation:

1. People’s Friendship University of Russia, First Moscow State Medical University n.a. I.M. Sechenov

Abstract

The article presents data on the clinical and contraceptive capabilities of an estrogen-progestogen drug containing drospirenone (Midiana). By its pharmacological properties, drospirenone is close to endogenous progesterone and has gestagenic, antiandrogenic and antimineralocorticoid action. With a high affinity for progesterone receptors, drospirenone suppresses ovulation, reliably protects against unwanted pregnancy and provides an additional contraceptive effect. Combined oral contraceptives with drospirenone, taking into account their antiandrogenic and antimineralocorticoid properties, are successfully used in the treatment of premenstrual syndrome, polycystic ovaries, hyperandrogenism and in the prevention of endometrial hyperplastic processes without causing significant weight change.

Publisher

Alfmed LLC

Subject

Materials Chemistry,Economics and Econometrics,Media Technology,Forestry

Reference35 articles.

1. Christin-Maitre S. History of oral contraceptive drugs and their use worldwide. Best Pract Res Clin Endocrinol Metab 2013; 27 (1): 3–12. DOI: 10.1016/j.beem.2012.11.004.

2. IPPF Med Bull 1971; 5 (4): 4. Improved contraception in Hungary. 3. Szlendak-Sauer K, Radowicki S, Skórzewska K. The impact of a new low dose oral contraceptive containing drospirenone on lipid profile, carbohydrate metabolism and hepatic function. Ginekol Pol 2009; 80 (2): 99–102.

3. Prilepskaya V. N. Gormonal'naya kontratseptsiya. Klinicheskie lektsii. M. GEOTAR-media. 2014. S. 253.

4. Yakushevskaya O.V., Revazova Z.V. Effektivnaya kontratseptsiya v sovremennykh usloviyakh. RMZh. Mat' i ditya 2013; 23: 22–27.

5. Mezhevitinova E. A., Sasunova R. A., Ivanova E.A., Ledina A.V. Drospirenon v evolyutsii gormonal'noi kontratseptsii. Ginekologiya 2011; 13 (2): 16–19.