Epidemiology issues in problem of antibiotic resistance of clinical pathogens

Author:

Gabrielyan N. I.1,Sharapchenko S. O.1,Kisil O. V.2,Kormilitsina V. G.1,Drabkina I. V.1,Safonova T. B.3,Petrukhina M. I.3,Saitgareev R. Sh.1,Zakharevich V. M.1

Affiliation:

1. National Medical Research Centre for Transplantology and Artificial Organs n. a. academician V. I. Shumakov

2. Scientific Research Institute for the Research of New Antibiotics n. a. G. F. Gauze

3. Russian Medical Academy for Continuing Professional Education

Abstract

The relevance of the work is due to the increase in the number of hospital infections associated with antibiotic-resistant gram-negative pathogens on a global scale. For medical institutions, both from a clinical and economic point of view, the catastrophic situation is that the multidrug-resistant pathogens increasing leads to limited possible treatment options. Analysis of published scientific articles shows that today the strict epidemiological surveillance and the study of the pathogen resistance profile in each medical facility is an effective tool for controlling the growth of multidrug-resistant microorganisms, thus reducing morbidity and mortality.

Publisher

Alfmed LLC

Subject

Materials Chemistry,Economics and Econometrics,Media Technology,Forestry

Reference19 articles.

1. Tacconelli E, Carrara E, Savoldi A, et al. Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis. Lancet Infect. 2018; 18 (3): 318–327. DOI: 10.1016/S14733099(17)30753–3.

2. Brink AJ. Epidemiology of carbapenem-resistant Gram-negative infections globally. Curr Opin Infect Dis. 2019; 32 (6): 609–616. DOI: 10.1097/QCO.0000000000000608.

3. Rudnov V. A., Kolotova G. B., Bagin V. A., et al. The role of antimicrobial therapy management in the resuscitation and intensive care service of a multidisciplinary hospital. Clinical microbiology and antimicrobial chemotherapy. 2018: 20 (2): 132–14 (In Russ.)

4. La Fauci V, Costa GB, Arena A, et al. Trend of MDR-microorganisms isolated from the biological samples of patients with HAI and from the surfaces around that patient. New Microbiol. 2018; 41 (1): 42–46.

5. Nordmann P, Poirel L. Epidemiology and diagnostics of carbapenem resistance in gram-negative bacteria. Clin Infect Dis. 2019; 69: S 521S 528. DOI: 10.1093/cid/ciz824.

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