Affiliation:
1. National Medical Research Centre n. a. V. A. Almazov
Abstract
Data from an original study evaluating the efficacy and safety of doxylamine in the treatment of insomnia in cardiac patients are presented. Materials and methods. Ten patients with sleep disorders were under observation. Doxylamine-SZ was prescribed to 10 patients (seven women and three men aged 40 to 60 years) who consulted a cardiologist with sleep disturbances from 2 to 7 times a week in the last month. Patients received Doxylamine-SZ at a dose of 1/2 tablet 15 mg 30 minutes before bedtime. Six patients noted normalization of sleep after 2–3 days of taking the drug and discontinued the drug, four patients who had insufficient clinical effect, the dose of the drug was increased to a whole 15 mg tablet. After 5 days of therapy, an improvement in the quality of sleep was noted in 80 % of patients. Conclusions. Doxylamine-SZ at a dosage of 15 mg 30 minutes before bedtime can be assessed as a safe and effective hypnotic in a cardiac patient.
Subject
Materials Chemistry,Economics and Econometrics,Media Technology,Forestry