GUT BARRIER FUNCTION IN YOUNG CHILDREN WITH FOODALLERGY AND CAPABILITIES OF SPECIALIZED AMINO ACIDBASED FORMULAS USAGE

Author:

Makarova S G,Borovik T E,Yatsyk G V,Zvonkova N G,Makarova S,Borovik T,Yatsyk G,Zvonkova N

Abstract

The article includes a brief literature review of clinical and experimental studies of intestinal uptake and absorption of macromolecules. Results of own research of the gut permeability for human milk α-lactalbumin in premature infants (30-36 weeks) are presented. The study revealed a reduction of gut permeability during the first months of life regardless of gestation age and type of feeding. Absorption of human milk α-lactalbumin did not decrease in babies with allergy symptoms, which appeared during the first month after birth. Study of gut barrier function in infants with skin and gastrointestinal manifestations of food allergy has shown maintenance and further increasing of intestinal permeability for human α-lactalbumin during the first year of life. In this regard, the indications for the use of specialized amino acids based formula Neocate were considered and the results of its application were presented.

Publisher

Farmarus Print Media

Reference46 articles.

1. Vighi G., Marcucci F., Sensi L. et al. Allergy and the gastrointestinal system. Clin Exp Immunol. 2008 Sep, 153 Suppl 1, p. 3-6.

2. Harry Wichers. Immunomodulation by food: promising concept for mitigating allergic disease? Received March 26, 2009. Revised April 30, 2009.

3. Gourbeyre P., Denery S., Bodinier M. Probiotics, prebiotics, and synbiotics: impact on the gut immune system and allergic reactions. J. Leukoc Biol. 2011, Jan 13.

4. Балаболкин И.И., Мазо В.К., Никитина И.П., Саменкова Н.Ф. Всасывание белковых антигенов в желудочно-кишечном тракте при пищевой аллергии у детей. Педиатрия. 1988, № 5, с. 52-54.

5. Балаболкин И.И., Карсыбекова Л.М., Гершман Г.Б. и соавт. Морфофункциональные изменения тонкой кишки у детей с пищевой аллергией. Педиатрия. 1991, № 1, с. 38-42.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3