Author:
Gushchin I S,Danilicheva I V
Abstract
Data on pharmacokinetics and pharmacodynamics, efficacy and safety of ebastin, a review of clinical studies of therapy of allergic rhinitis, chronic idiopathic urticaria and other dermatoses are presented.
Reference55 articles.
1. Rico S, Antonijoan RM, Barbanoj MJ. Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines Journal of Asthma and Allergy. 2009;2:73-92.
2. Гущин ИС. Аллергическое воспаление и его фармакологический контроль. М.; «Фармарус Принт», 1998. 252 с.
3. Liu KH, Kim MG, Lee D, Yoon YJ, Kim MJ, Shon JH et al. Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: major roles for CYP2J2 and CYP3A. Drug Metabolism and Disposition. 2006;34:1793-1797.
4. Гущин ИС. Обратные агонисты Н1-рецепторов как перспективные противоаллергические средства (обзор). Химикофармацевтический журнал. 2010:(1):8388.
5. Wiseman LR, Faulds D. Ebastine. A review of its pharmacological properties and clinical efficacy in the treatment of allergic disorders. Drugs. 1996;51:260-277.