Abstract
The paper is devoted to the assessment of the relationship between regional life expectancy at birth (LE) with a number of economic and sociodemographic factors, in particular the gross regional product (GRP) and the share of urban population residing in large cities in the total population of the region. The analysis shows that the economic factor has a strong positive correlation with LE, especially in regions with unfavorable climatic conditions. The proportion of urban population residing in large cities in the total population of the region, influencing LE through improved health infrastructure and greater accessibility of health services to urban residents, merely complements the leading role of the economic factor.