Ahead of a vaccine: A safe method of protection against COVID-19 exists

Abstract

In the case of current COVID-19, successful prophylactic approaches are likely to have a greater impact than successful treatment approaches. In this article, we discuss the challenges before the creation of anti-SARS-CoV-2 vaccines and opportunities of other means that can enhance non-specific immunity focusing on interferon in particular. Since efficacy of intranasal interferons against a number of pathogens throughout a period of 37 years and against COVID-19 as well as safety have been shown, this method of protection can be introduced in a short period while using a permitted off-label application approach.