Liquid chromatography – high resolution mass spectrometry screening of Astragalus hamosus and Astragalus corniculatus

Author:

Shkondrov AleksandarORCID,Krasteva IlinaORCID

Abstract

Astragalus hamosus and Astragalus corniculatus were examined for the presence of flavoalkaloids, acylated and highly glycosylated flavonoids. Non-purified extracts of the overground parts of the species were subjected to ultra-high performance liquid chromatography – high resolution electrospray ionisation mass spectrometry (UHPLC-HRESIMS) analysis and the results were compared to authentic reference substances. A flavoalkaloid of kaempferol was newly identified in an extract of A. hamosus. In addition, three compounds – quercetin and kaempferol flavonoids, acylated with hydroxymethylglutaric acid and alcesefoliside, were found in extracts of A. hamosus and A. corniculatus for the first time.

Publisher

Pensoft Publishers

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacy

Reference23 articles.

1. In vitro antineoplastic activity of some cytoreductive drugs versus new compounds of plant origin.;Dineva;International Journal of Current Chemistry,2010

2. Transformation ofAstragalusSpecies byAgrobacterium rhizogenesand their Saponin Production

3. Astragalus Species (Milk Vetch): In Vitro Culture and the Production of Saponins, Astragaline, and Other Biologically Active Compounds

4. Antiproliferative effects of a flavonoid and saponins from Astragalus hamosus against human tumor cell lines.;Krasteva;Pharmacognosy Magazine,2008

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3