Analysis of adherence and factors affecting insulin therapy outcomes in outpatients with Diabetes Mellitus

Author:

Dwiyatna Surya,Suprapti BudiORCID,Nilamsari Wenny Putri,Nugroho Cahyo Wibisono,Ardiana Shafira Muti

Abstract

Background: Insulin is an effective diabetes treatment for outpatients with Diabetes Mellitus (DM) to maximize medication therapy. However, the level of insulin adherence is still low. This study aims to analyze adherence, glycemic control, and factors that influence the achievement of insulin therapy in Type 2 Diabetes Mellitus (T2DM) outpatients. Methods: This study was a cross-sectional study conducted on T2DM outpatients. Adherence to Refills and Medications Scale (ARMS) and Diabetes Knowledge Questionnaire (DKQ) were used to assess patients’ adherence and knowledge of insulin use. Multiple logistic regression tests were carried out to measure the effect of factors on adherence and insulin therapy outcomes. Results: Of the 141 patients adherence to insulin treatment was found to be 33.3%. Patients who achieved glycemic control assessed by Glycosylated Haemoglobin (HbA1c), Fasting Blood Glucose (FBG), and Two hours of Postprandial Blood Glucose (2hPPBG) were 36.2%, 39%, and 43.3%. The duration of insulin use had a significant effect on adherence (p-value 0.013) and 2hPPBG target (p-value 0,049), while other factors had no significance. Conclusion: Adherence to insulin therapy and glycemic control targets were found to be low. The duration of insulin use was associated with medication adherence and insulin therapy outcomes.

Publisher

Pensoft Publishers

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