Scaling of organ masses in mammals and birds: phylogenetic signal and implications for metabolic rate scaling

Abstract

The persistent enigma of why the whole-body metabolic rate increases hypoallometrically with body mass should be solved on both the ultimate and proximate levels. The proximate mechanism may involve hyperallometric scaling of metabolically inert tissue/organ masses, hypoallometric scaling of metabolically expensive organ masses, a decrease in mass-specific metabolic rates of organs or a combination of these three factors. Although there are literature data on the tissue/organ masses scaling, they do not consider phylogenetic information. Here, we analyse the scaling of tissue/organ masses in a sample of 100 mammalian and 22 bird species with a phylogenetically informed method (PGLS) to address two questions: the role of phylogenetic differences in organ/tissue size scaling and the potential role of organ/tissue mass scaling in interspecific metabolic rate scaling. Strong phylogenetic signal was found for the brain, kidney, spleen and stomach mass in mammals but only for the brain and leg muscle in birds. Metabolically relatively inert adipose tissue scales isometrically in both groups. The masses of energetically expensive visceral organs scale hypoallometrically in mammals, with the exception of lungs, with the lowest exponent for the brain. In contrast, only brain mass scales hypoallometrically in birds, whereas other tissues and organs scale isometrically or almost isometrically. Considering that the whole-body metabolic rate scales more steeply in mammals than in birds, the mass-specific metabolic rate of visceral organs must decrease with body mass much faster in birds than in mammals. In general, studying whole-body metabolic rate is not adequate for explaining its scaling, and measuring metabolic rates of organs, together with their contribution to body mass, is urgently required.