An infographic model of a database for conducting an analytical study of the long-term consequences of cervical cancer treatment

Abstract

Relevance. The development of ideas of critical attitude to medical information led to the concepts of evidence-based medicine (EM) in the late 1980s. The main postulates of EM are following: – every doctor’s decision must be based on scientific data; – the weight of each fact is greater, the stricter the method of scientific research in the course of which it was obtained. Correct planning of the research design and qualified statistical analysis are the most important for obtaining reliable, scientifically based results. The application of modern information technologies to arrays of catamnetic data of patients with cervical cancer (CRC) provides an opportunity to conduct a scientific study on the detection of the dependence of the appearance of oncological consequences of CRC treatment (metastases, relapses, secondary cancers) and manifestations of radiation toxicity on the clinical and biological characteristics of the patient and the features of the performed chemoradiation treatment. A necessary component of the success of such research is strict adherence to the principles of evidence-based medicine at all stages, in particular research planning. The main task at this stage is to determine the informative constitutional and biological, biometric, and social characteristics of the patient, parameters of treatment and the development of the disease in order to create a relevant informational model of the research database. The purpose of the work is to create an infological model of the catamnetic database of patients with CRC in order to determine the risk factors of local and distant metastasis and radiation toxicity during radical chemoradiation treatment of patients with CRC. Materials and methods: scientific literature with a level of evidence of primary data not lower than 2+, analysis of own experience, specialized analytical system «Database of patients». Results and discussion. An infological model of the database of catamnetic data of patients with CRC has been created, which provides the most complete representation of the subject area, contains all the entities and their attributes necessary for implementation. It is shown which parameters, factors and features of the disease should be taken into account when creating a database to obtain informationally significant results based on the accumulated data. Conclusions. The relevant informational model of the research database created in accordance with the approaches of evidence-based medicine is a necessary component for obtaining scientifically based results based on the catamnetic data of patients with CRC.