Affiliation:
1. Department of Pathology, University of Washington School of Medicine Seattle, Washington 98195.
Abstract
The relations between end-diastolic (
D
) and end-systolic (S) cavitary volumes (
V
c
), wall volumes (
V
10
), and cavitary dimensions have been studied in the canine and human left ventricle. However, the models selected for left ventricular myocardium do not represent the real heart adequately for a fiber-by-fiber analysis of fiber orientation and sarcomere length during successive states of the ejection cycle. In this study, the endocardial and epicardial surfaces were postulated to be a nested set of truncated ellipsoidal shells of revolution where wall volumes were preserved from
D
to S. Shell dimensions on the semiminor and semimajor axes,
R
and
Z
, respectively, were related to
V
c
and
V
w
by two representations: confocal and nonconfocal. If the focal length
C
= )
1/2
and
C
is the same for each shell, then the shells are confocal, otherwise they are nonconfocal. From measured
V
c
,
V
w
, and epicardial
Z
in
D
, shell dimensions were calculated for states
D
and S, using both confocal and nonconfocal representations, and compared with the measured dimensions. When no empirical corrections were made, the calculated endocardial
R
in S underestimated the measured
R
in S by 12%; moreover, the calculated epicardial
R
in S overestimated the measured
R
in S by 4%. Endocardial and epicardial C measured 3.73 ± 0.33 (SE) cm and 3.79 ±0.34 cm, respectively, in
D
and 3.77±0.11 cm and 3.71 ±0.10 cm, respectively, in S.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Cardiology and Cardiovascular Medicine,Physiology
Cited by
137 articles.
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