Pacemaker Periodicity in Atrial Fibrillation

Author:

BATTERSBY EDWARD J.1

Affiliation:

1. Department of Medicine and Physiology, Vanderbilt University School of Medicine, Nashville, Tennessee

Abstract

The presence of a periodic component in the atrial waveform of patients with chronic atrial fibrillation can be demonstrated by the use of autocorrelation techniques, and is interpreted as evidence for the presence of a periodic or almost periodic pacemaking mechanism. In twelve patients the average rate of this periodic element was 421 per minute with a range of 346 to 528. No correlation is present between increasing rate and disorder of the waveform. The presence of persistent random wavelets modifying the beat-to-beat spread of excitation generated by a periodic focal pacemaker is proposed as a unifying hypothesis explaining the variability of the atrial waveform in atrial fibrillation in man.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

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