Thixotropy of Blood and Proneness to Thrombus Formation

Author:

Dintenfass Leopold1

Affiliation:

1. Surgical Research Unit, Prince of Wales Division, Sydney Hospital, Randwick, Australia

Abstract

A study of the viscosity and thixotropy of human blood in the absence of anticoagulants was carried out by means of a rotational cone-in-cone viscometer. The plots of viscosity against the rate of shear on a log-log scale show that the thixotropy of normal blood is pronounced only below 5 sec. -1 ; abnormally thixotropic blood was characterized by the critical rates of shear of 30 to 60 sec. -1 . The significance of thixotropy of blood is due to its intimate relationship with the aggregation of red cells. It is suggested that it may be also related to the proneness of thrombus formation.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference19 articles.

1. COPLEY A. L. AND STAINSBY G.: Flow Properties of Blood. New York Pergamon Press 1900.

2. Rheology of blood and Iymph. In Deformation and Flow in Biological Systems, edited by A. Frey-Wyssling. Amsterdam;BAYLISS L. E.;North Holland Publishing Co.,1952

3. BRUNDAGE J . T.: Blood and plasma viscosity determined by the method of

4. Shear Rate Dependence of the Viscosity of Whole Blood and Plasma

5. Measurement of viscosity of biological fluids by cone plate viscometer;WELLS R. E.;J. Lab. & Clin. Med.,1961

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