Effects of Bradykinin on the Systemic and Coronary Vascular Bed of the Intact Dog-Reference-Cited by-同舟云学术

Effects of Bradykinin on the Systemic and Coronary Vascular Bed of the Intact Dog

Published:1962-03 Issue:3 Volume:10 Page:359-363
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circulation Research

Author:

MAXWELL G. M.¹,ELLIOTT R. B.¹,KNEEBONE G. M.¹

Affiliation:

1. Department of Child Health, University of Adelaide, Adelaide Children's Hospital, Inc., North Adelaide, South Australia

Abstract

Bradykinin, in the circumstances of this study, increased heart rate, cardiac output, and coronary blood flow. Systemic, pulmonary, and coronary vascular resistances decreased; these changes were not entirely due to the decrease in systemic and pulmonary arterial pressures. The changes in myocardial oxygen and carbon dioxide metabolism were mostly related to the increase in coronary blood flow. Bradykinin was found to be associated with a decrease in cardiac efficiency.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.RES.10.3.359

Reference15 articles.

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3. Actions of pure bradykinin

4. Bradykinin as a vaso-clilator in man;GOLDSMITH R.;J. Physiol.

5. Effect of Bradykinin in an isolated perfused dog-lung preparation;WAALER B. A.;J. Physiol.

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