Left Ventricular Function in Mammals of Greatly Different Size

Author:

Holt J. P.1,Rhode E. A.1,Peoples S. A.1,Kines Helga1

Affiliation:

1. Heart Research Laboratory, University of Louisville School of Medicine, Louisville, Kentucky, and School of Veterinary Medicine, University of California, Davis, California

Abstract

Studies of left ventricular volume and pressure have been carried out in the control state in four classes of intact anesthetized mammals (horses, cattle, swine, and dogs), body weights of which varied 54-fold. On the basis of these studies of both large and small hearts, extending over a wide range, a pattern of function for the left ventricle of all mammals has been described. Mathematical equations are given describing the interrelationships between left ventricular end-diastolic volume and end-systolic volume, stroke volume, cardiac output, stroke-work, heart rate, and total peripheral resistance.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference14 articles.

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2. QUIRING D. P.: Functional Anatomy of tlio Vertebrates. New York McGraw-Hill Book Co. Inc. 1950.

3. Relation of heart size to the time intervals of the heart beat, with particular reference to the elephant and the whale. New England .1;WHITE P. D.;Med.,1953

4. HOI.T J. P.: Estimation of the residual volume of the ventricle of the dog's heart by two indicator dilution technics. Circulation Research 4: 187 195G.

5. Effect of Plethora and Hemorrhage on Left Ventricular Volume and Pressure

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