Role of Vasoconstriction in Experimental Arteriosclerosis

Author:

Gutstein William H.1,LaTaillade Jean N.1,Lewis Leon1

Affiliation:

1. Department of Pathology, New York University School of Medicine, New York, New York

Abstract

A method is given for the study of local neuroexcitation with subsequent vasoconstriction and its relationship to experimental arteriosclerosis in unanesthetized animals under normal laboratory conditions. Histological observations of vasoactive areas of stimulated blood vessels in the laboratory rat disclose some of the features observed elsewhere in experimental arteriosclerosis. Possible pathogenic mechanisms relating neurostimulation of autonomic arterial nerves with in situ arteriopathies are discussed.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

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