1. From the Donald W. Reynolds Cardiovascular Clinical Research Center, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass (K.C., G.K.S., R.R.S.P., P.L.); University Hospitals Case Medical Center, Case Cardiovascular Center, Case Western Reserve University School of Medicine, Cleveland, Ohio (K.C., H.G., Y.W., T.M., M.S., C.S., D.I.S.); Cancer Research UK, London, England (N.H.); and VA Boston Healthcare System, Boston, Mass (K.C.).