1. From the Department of Cardiovascular Sciences, Texas Methodist Hospital Research Institute, Houston (Y.T.G., J.P.C.); Department of Medicine (P.L., J.C.L., N.H.S.) and SPARK Translational Research Program (D.A.E.), Stanford University, Stanford, CA; and Nitric Oxide Signaling Group, MRC Clinical Sciences Center, Imperial College London, London, UK (A.S., J.L.).