1. From the Department of Molecular Cardiology (N.T.V., M.L.M., M.K.G., E.E.M., A.K.H., Y.Q., D.Y., S.S., S.V.N.P.), Cell Biology (U.M.C., P.E.D.), Lerner Research Institute, Cleveland Clinic, Cleveland, OH; Temple University School of Medicine, Temple University, Philadelphia, PA (A.M.F.); and Center for Pharmacogenomics, Washington University, St. Louis, MO (G.W.D.).